Amphiphysin (AMPH) Antibody

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

Target	Amphiphysin (AMPH)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 140-168 amino acids from the Central region of human AMPH.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49418 (UniProt, ExPASy)
UniProt Secondary AC	A4D1X8, A4D1X9, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0
UniProt Entry Name	AMPH_HUMAN
KEGG	hsa:273
String	9606.ENSP00000348602
Molecular Weight	Calculated MW: 76.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat AMPH.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Amphiphysin (AMPH)

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