Amphiphysin (AMPH) Antibody

AMPH Antibody is a Rabbit Polyclonal antibody against AMPH. This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

Target	Amphiphysin (AMPH)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human AMPH.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49418 (UniProt, ExPASy)
UniProt Secondary AC	A4D1X8, A4D1X9, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0
UniProt Entry Name	AMPH_HUMAN
Gene Symbol	AMPH
GeneID	273
NCBI Accession	NP_001626.1
KEGG	hsa:273
String	9606.ENSP00000348602
Molecular Weight	Calculated MW: 76 kDa Observed MW: 125 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Amphiphysin (AMPH)

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