Anaphase-Promoting Complex Subunit 4 (ANAPC4) Antibody

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq].

Target	Anaphase-Promoting Complex Subunit 4 (ANAPC4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 638-664 amino acids from the Central region of human ANAPC4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UJX5 (UniProt, ExPASy)
UniProt Secondary AC	A8K8H1, E9PCR4, Q6PCC6, Q9NSH6
UniProt Entry Name	APC4_HUMAN
Gene Symbol	ANAPC4
String	9606.ENSP00000426654
Molecular Weight	Calculated MW: 92.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Anaphase-Promoting Complex Subunit 4 (ANAPC4)

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