Anaphase Promoting Complex Subunit 5 (ANAPC5) Antibody

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Catalogue No: abx026017
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Target Anaphase Promoting Complex Subunit 5 (ANAPC5)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UJX4 (UniProt, ExPASy)
UniProt Secondary AC E9PFB2, Q8N4H7, Q9BQD4
UniProt Entry Name APC5_HUMAN
Gene Symbol ANAPC5
String 9606.ENSP00000261819
Molecular Weight Calculated MW: 85.1 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Anaphase Promoting Complex Subunit 5 (ANAPC5)


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