+44 (0) 1223 755950
+1 832 327 7413
Androgen Receptor (AR) Antibody
REQUEST MORE INFO
Catalogue No: abx011626
Price:
US$420.50
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Research Articles on Androgen Receptor (AR)
| Target | Androgen Receptor (AR) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human AR expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10275 (UniProt, ExPASy) |
| UniProt Secondary AC | A0A0B4J1T2, A2RUN2, B1AKD7, C0JKD3, C0JKD4, E7EVX6, Q9UD95 |
| UniProt Entry Name | ANDR_HUMAN |
| Gene Symbol | AR |
| GeneID | 367 |
| OMIM | 300068 |
| HGNC | 644 |
| KEGG | hsa:367 |
| Ensembl | ENSG00000169083 |
| String | 9606.ENSP00000363822 |
| Molecular Weight | 110 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |