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Introduction | Angiotensin (AGT, also known as SERPINA8) is a peptide hormone that causes vasoconstriction. It is produced from a precursor protein, angiotensinogen, from which 8 known forms of angiotensin may be formed: Ang I, Ang II, Ang III, Ang IV, Ang 1-9, Ang 1-7, Ang 1-5, and Ang 1-4. Angiotensin I has little biological activity, but can be processed into one of the other peptides, which may cause vasoconstriction, steroid hormone release, increased thirst, increased adipose development, and altered glomerular filtration rate. Dysregulation of angiotensin peptides is associated with cardiovascular disease and diabetes-related kidney disorders. |
Target | Angiotensin 1-7 (Ang 1-7) |
Reactivity | Human |
Tested Applications | CLIA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Test Range | 1.56 pg/ml - 400 pg/ml |
Sensitivity | < 0.64 pg/ml |
Standard Form | Lyophilized |
Detection Method | Chemiluminescent |
Assay Type | Competitive |
Assay Data | Quantitative |
Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Availability | Shipped within 5-7 working days. |
Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Standard | 400 pg/ml |