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Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2) Antibody
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Catalogue No: abx026947
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2)
| Target | Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 307-336 amino acids from the Central region of human APBA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99767 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PGI4, O60571, Q5XKC0 |
| UniProt Entry Name | APBA2_HUMAN |
| Gene Symbol | APBA2 |
| KEGG | hsa:321 |
| String | 9606.ENSP00000453293 |
| Molecular Weight | Calculated MW: 82.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat APBA2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |