Acylamino-Acid-Releasing Enzyme (APEH) Antibody

APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.

Target	Acylamino-Acid-Releasing Enzyme (APEH)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 174-204 amino acids from the N-terminal region of human APEH.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13798 (UniProt, ExPASy)
UniProt Secondary AC	Q9BQ33, Q9P0Y2
UniProt Entry Name	ACPH_HUMAN
Gene Symbol	APEH
GeneID	327
OMIM	102645
KEGG	hsa:327
String	9606.ENSP00000296456
Molecular Weight	Calculated MW: 81.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Acylamino-Acid-Releasing Enzyme (APEH)

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