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Apoptosis Inhibitor 5 (API5) Antibody
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Catalogue No: abx030586
Price:
US$326.25
(Size: 80 µl)
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Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Research Articles on Apoptosis Inhibitor 5 (API5)
| Target | Apoptosis Inhibitor 5 (API5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human API5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BZZ5 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DGR0, B4DRJ2, B4E283, D3DR21, O15441, Q9Y4J7 |
| UniProt Entry Name | API5_HUMAN |
| Gene Symbol | API5 |
| String | 9606.ENSP00000431391 |
| Molecular Weight | Calculated MW: 59 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |