Apolipoprotein A1 (APOA1) Antibody

APOA1 Antibody is a Rabbit Polyclonal antibody against APOA1. This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.

Target	Apolipoprotein A1 (APOA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-267 of human APOA1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02647 (UniProt, ExPASy) Q00623 (UniProt, ExPASy)
UniProt Secondary AC	A8K866, Q6LDN9, Q6Q785, Q9UCS8, Q9UCT8, O08855, O09042, Q8BPD5
UniProt Entry Name	APOA1_HUMAN, APOA1_MOUSE
Gene Symbol	APOA1
GeneID	335 11806
OMIM	107680
NCBI Accession	NP_000030.1
HGNC	600
Ensembl	ENSG00000118137, ENSMUSG00000032083
String	9606.ENSP00000236850 10090.ENSMUSP00000034588
Molecular Weight	Calculated MW: 28 kDa Observed MW: 29 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Apolipoprotein A1 (APOA1)

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