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Apoa5 (ab) Antibody
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Catalogue No: abx010415
Price:
US$427.75
(Size: 100 µl)
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Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Research Articles on Apoa5 (ab)
| Target | Apoa5 (ab) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6Q788 (UniProt, ExPASy) |
| UniProt Secondary AC | B0YIV9, Q3MIK6, Q6UWK9, Q9UBJ3 |
| UniProt Entry Name | APOA5_HUMAN |
| Gene Symbol | APOA5 |
| GeneID | 116519 |
| OMIM | 144650 |
| HGNC | 17288 |
| KEGG | hsa:116519 |
| Ensembl | ENSG00000110243 |
| String | 9606.ENSP00000445002 |
| Molecular Weight | 41 kDa |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |