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Apolipoprotein A-V (APOA5) Antibody
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Catalogue No: abx000061
Price:
US$217.50
(Size: 20 µl)
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APOA5 Antibody is a Rabbit Polyclonal antibody against APOA5. Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum.This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.
Research Articles on Apolipoprotein A-V (APOA5)
| Target | Apolipoprotein A-V (APOA5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 207-366 of human APOA5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6Q788 (UniProt, ExPASy) |
| UniProt Secondary AC | B0YIV9, Q3MIK6, Q6UWK9, Q9UBJ3 |
| UniProt Entry Name | APOA5_HUMAN |
| Gene Symbol | APOA5 |
| GeneID | 116519 |
| NCBI Accession | NP_443200.2 |
| KEGG | hsa:116519 |
| String | 9606.ENSP00000445002 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 41 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |