B-Cell CLL/Lymphoma 2 Like Protein 2 (BCL2L2) Antibody

B-Cell CLL/Lymphoma 2 Like Protein 2 (BCL2L2) Antibody is a Rabbit Polyclonal antibody for the detection of BCL2L2.

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding protein, nuclear 1) gene.

Target	B-Cell CLL/Lymphoma 2 Like Protein 2 (BCL2L2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	BCL2-like 2
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q92843 (UniProt, ExPASy)
UniProt Secondary AC	A8K0F4, Q2M3U0, Q5U0H4
Gene Symbol	BCL2L2
GeneID	599
OMIM	601931
HGNC	995
Ensembl	ENSG00000129473
Molecular Weight	Observed MW: 21 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on B-Cell CLL/Lymphoma 2 Like Protein 2 (BCL2L2)

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