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Adenine Phosphoribosyltransferase (APRT) Antibody
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Catalogue No: abx004177
Price:
US$217.50
(Size: 20 µl)
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APRT Antibody is a Rabbit Polyclonal antibody against APRT. Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Adenine Phosphoribosyltransferase (APRT)
| Target | Adenine Phosphoribosyltransferase (APRT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P07741 (UniProt, ExPASy) |
| UniProt Secondary AC | G5E9J2, Q3KP55, Q68DF9 |
| UniProt Entry Name | APT_HUMAN |
| Gene Symbol | APRT |
| GeneID | 353 |
| NCBI Accession | NP_000476.1 |
| KEGG | hsa:353 |
| String | 9606.ENSP00000367615 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |