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Amphiregulin (AREG) Antibody
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Catalogue No: abx001536
Price:
US$203.00
(Size: 20 µl)
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AREG Antibody is a Rabbit Polyclonal antibody against AREG. Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs.
Research Articles on Amphiregulin (AREG)
| Target | Amphiregulin (AREG) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human Amphiregulin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15514 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5U026 |
| UniProt Entry Name | AREG_HUMAN |
| Gene Symbol | AREG |
| GeneID | 374 |
| NCBI Accession | NP_001648.1 |
| KEGG | hsa:374 |
| String | 9606.ENSP00000379097 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |