Arg-Binding Protein 2 (ARGBP2) Antibody

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

Target	Arg-Binding Protein 2 (ARGBP2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O94875 (UniProt, ExPASy)
UniProt Entry Name	SRBS2_HUMAN
NCBI Accession	NP_001139142.1 NP_001139143.1 NP_001139144.1 NP_001139145.1 NP_001139146.1 NP_001257700.1 NP_003594.3 NP_066547.1
KEGG	hsa:8470
String	9606.ENSP00000347852
Molecular Weight	Calculated MW: 124 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Pig SORBS2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Arg-Binding Protein 2 (ARGBP2)

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