+44 (0) 1223 755950
+1 832 327 7413
Rho-Related GTP-Binding Protein RhoE (ARHE) Antibody
REQUEST MORE INFO
Catalogue No: abx033659
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925) ; GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855) ; and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).
Research Articles on Rho-Related GTP-Binding Protein RhoE (ARHE)
| Target | Rho-Related GTP-Binding Protein RhoE (ARHE) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61587 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DP95, P52199 |
| UniProt Entry Name | RND3_HUMAN |
| KEGG | hsa:390 |
| String | 9606.ENSP00000364886 |
| Molecular Weight | Calculated MW: 27.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig RND3. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |