Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Antibody

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Catalogue No: abx029162
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Target Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15085 (UniProt, ExPASy)
UniProt Secondary AC D3DVD0, Q5VY40, Q6PFW2
UniProt Entry Name ARHGB_HUMAN
Gene Symbol ARHGEF11
KEGG hsa:9826
String 9606.ENSP00000357177
Molecular Weight Calculated MW: 168 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat ARHGEF11.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11)


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