Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Antibody

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Target	Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 249-278 amino acids from the Central region of human ARNT2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HBZ2 (UniProt, ExPASy)
UniProt Secondary AC	B4DIS7, O15024, Q8IYC2
UniProt Entry Name	ARNT2_HUMAN
Gene Symbol	ARNT2
String	9606.ENSP00000307479
Molecular Weight	Calculated MW: 78.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat ARNT2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2)

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