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Arrestin Beta 1 (ARRB1) Antibody
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Catalogue No: abx000951
Price:
US$348.00
(Size: 60 µl)
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ARRB1 Antibody is a Rabbit Polyclonal antibody against ARRB1. Members of ARRB1/beta-ARRB1 protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-ARRB1 system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of ARRB1 have been described.
Research Articles on Arrestin Beta 1 (ARRB1)
| Target | Arrestin Beta 1 (ARRB1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/20 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ARRB1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49407 (UniProt, ExPASy) |
| UniProt Secondary AC | B6V9G8, O75625, O75630, Q2PP20, Q9BTK8 |
| UniProt Entry Name | ARRB1_HUMAN |
| Gene Symbol | ARRB1 |
| GeneID | 408 |
| NCBI Accession | NP_004032.2 |
| KEGG | hsa:408 |
| String | 9606.ENSP00000409581 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
