Asialoglycoprotein Receptor 1 (ASGR1) Antibody

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Catalogue No: abx028618
Price: US$326.25
(Size: 80 µl)

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Asialoglycoprotein Receptor 1 (ASGR1) Antibody
Asialoglycoprotein Receptor 1 (ASGR1) Antibody

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Datasheet SDS
Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Target Asialoglycoprotein Receptor 1 (ASGR1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07306 (UniProt, ExPASy)
UniProt Secondary AC I3L1X1
UniProt Entry Name ASGR1_HUMAN
Gene Symbol ASGR1
GeneID 432
OMIM 108360
HGNC 742
KEGG hsa:432
Ensembl ENSG00000141505
String 9606.ENSP00000269299
Molecular Weight Calculated MW: 33.2 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Asialoglycoprotein Receptor 1 (ASGR1)
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