Cyclic AMP-Dependent Transcription Factor ATF-4 (ATF4) Antibody

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Catalogue No: abx026679
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Target Cyclic AMP-Dependent Transcription Factor ATF-4 (ATF4)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 171-198 amino acids from the Central region of human ATF4.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18848 (UniProt, ExPASy)
UniProt Secondary AC Q96AQ3, Q9UH31
Gene Symbol ATF4
NCBI Accession NP_001666.2 NP_877962.1
KEGG hsa:468
String 9606.ENSP00000336790
Molecular Weight Calculated MW: 38.6 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Cyclic AMP-Dependent Transcription Factor ATF-4 (ATF4)
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