ATF4 (pS245) Antibody

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Catalogue No: abx000357
Price: US$333.50
(Size: 100 µl)
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Western blot analysis of lysates from HeLa cells using Phospho-ATF4-S245 Antibody. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% BSA.
ATF4 (pS245) Antibody

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Datasheet SDS
ATF4 (pS245) Antibody is a Rabbit Polyclonal antibody against ATF4 (pS245). This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Target ATF4 (pS245)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A phospho specific peptide corresponding to residues surrounding S245 of human ATF4
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18848 (UniProt, ExPASy)
UniProt Secondary AC Q96AQ3, Q9UH31
Gene Symbol ATF4
GeneID 468
KEGG hsa:468
String 9606.ENSP00000336790
Molecular Weight Calculated MW: 39 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on ATF4 (pS245)
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