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Ubiquitin-Like Protein ATG12 (ATG12) Antibody
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Catalogue No: abx030073
Price:
US$326.25
(Size: 80 µl)
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Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.
Research Articles on Ubiquitin-Like Protein ATG12 (ATG12)
| Target | Ubiquitin-Like Protein ATG12 (ATG12) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ATG12. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O94817 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6PJV2 |
| UniProt Entry Name | ATG12_HUMAN |
| Gene Symbol | ATG12 |
| GeneID | 9140 |
| OMIM | 609608 |
| NCBI Accession | NP_001264712.1 NP_004698.3 |
| HGNC | 588 |
| KEGG | hsa:9140 |
| Ensembl | ENSG00000145782 |
| String | 9606.ENSP00000425107 |
| Molecular Weight | Calculated MW: 15.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |