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Bifunctional Purine Biosynthesis Protein PURH (ATIC) Antibody
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Catalogue No: abx004258
Price:
US$217.50
(Size: 20 µl)
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ATIC Antibody is a Rabbit Polyclonal antibody against ATIC. This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Research Articles on Bifunctional Purine Biosynthesis Protein PURH (ATIC)
| Target | Bifunctional Purine Biosynthesis Protein PURH (ATIC) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ATIC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P31939 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K202, E9PBU3, Q13856, Q53S28 |
| UniProt Entry Name | PUR9_HUMAN |
| Gene Symbol | ATIC |
| GeneID | 471 |
| OMIM | 601731 |
| NCBI Accession | NP_004035.2 NM_004044.6 |
| HGNC | 794 |
| KEGG | hsa:471 |
| Ensembl | ENSG00000138363 |
| String | 9606.ENSP00000236959 |
| Molecular Weight | Calculated MW: 65 kDa Observed MW: 62 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 0.15 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |