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ATP Binding Cassette Transporter C6 (ABCC6) Antibody
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Catalogue No: abx240091
Price:
US$406.00
(Size: 100 µg)
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ATP Binding Cassette Transporter C6 (ABCC6) Antibody is a Rabbit Polyclonal antibody for the detection of ABCC6. The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).
Research Articles on ATP Binding Cassette Transporter C6 (ABCC6)
| Target | ATP Binding Cassette Transporter C6 (ABCC6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O95255 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRN8, A8KIG6, A8Y988, E7ESW8, P78420, Q8TCY8, Q9UMZ7 |
| UniProt Entry Name | MRP6_HUMAN |
| Gene Symbol | ABCC6 |
| GeneID | 368 |
| KEGG | hsa:368 |
| String | 9606.ENSP00000205557 |
| Molecular Weight | Observed MW: 165 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |