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ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A) Antibody
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Catalogue No: abx148411
Price:
US$406.00
(Size: 100 µg)
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ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A) Antibody is a Rabbit Polyclonal antibody for the detection of ATP5A1. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.
Research Articles on ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A)
| Target | ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P25705 (UniProt, ExPASy) |
| UniProt Entry Name | ATPA_HUMAN |
| Gene Symbol | ATP5F1A |
| GeneID | 498 |
| OMIM | 164360 |
| HGNC | 823 |
| KEGG | hsa:498 |
| Ensembl | ENSG00000152234 |
| String | 9606.ENSP00000381736 |
| Enzyme Commission Number | EC 3.6.3.14 |
| Molecular Weight | Observed MW: 54 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |