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ATPase, Na+/K+ Transporting Beta 3 Polypeptide (ATP1B3) Antibody
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Catalogue No: abx026991
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ ATPases. Na+/K+ ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq].
Research Articles on ATPase, Na+/K+ Transporting Beta 3 Polypeptide (ATP1B3)
| Target | ATPase, Na+/K+ Transporting Beta 3 Polypeptide (ATP1B3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human ATP1B3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54709 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z1N7 |
| UniProt Entry Name | AT1B3_HUMAN |
| KEGG | hsa:483 |
| String | 9606.ENSP00000286371 |
| Molecular Weight | Calculated MW: 31.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |