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ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Antibody
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Catalogue No: abx148424
Price:
US$406.00
(Size: 100 µg)
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ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Antibody is a Rabbit Polyclonal antibody for the detection of ATP2A2. This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2)
| Target | ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ATP2A2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P16615 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NDN7, B4DF05, P16614, Q86VJ2 |
| UniProt Entry Name | AT2A2_HUMAN |
| Gene Symbol | ATP2A2 |
| GeneID | 488 |
| OMIM | 108740 |
| HGNC | 812 |
| KEGG | hsa:488 |
| Ensembl | ENSG00000174437 |
| String | 9606.ENSP00000440045 |
| Molecular Weight | Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |