ATRIP (pS239) Antibody

The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	ATRIP (pS239)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8WXE1 (UniProt, ExPASy)
UniProt Entry Name	ATRIP_HUMAN
KEGG	hsa:84126
String	9606.ENSP00000323099
Molecular Weight	Calculated MW: 85.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey ATRIP.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATRIP (pS239)

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