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Ataxin 3 / ATX3 (ATXN3) Antibody
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Catalogue No: abx001155
Price:
US$203.00
(Size: 20 µl)
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ATXN3 Antibody is a Rabbit Polyclonal antibody against ATXN3. Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009].
Research Articles on Ataxin 3 / ATX3 (ATXN3)
| Target | Ataxin 3 / ATX3 (ATXN3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-361 of human Ataxin-3 (ATXN3). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54252 (UniProt, ExPASy) |
| UniProt Entry Name | ATX3_HUMAN |
| Gene Symbol | ATXN3 |
| GeneID | 4287 |
| NCBI Accession | NP_004984.2 |
| KEGG | hsa:4287 |
| String | 9606.ENSP00000478320 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 42 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |