Ancient Ubiquitous Protein 1 (AUP1) Antibody

This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha (IIb) subunits. These subunits play a crucial role in the integrin alpha (IIb) beta (3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

Target	Ancient Ubiquitous Protein 1 (AUP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y679 (UniProt, ExPASy)
UniProt Secondary AC	C0H5W8, Q9H866, Q9UNQ6, Q9Y685
UniProt Entry Name	AUP1_HUMAN
Gene Symbol	AUP1
Molecular Weight	Calculated MW: 45.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ancient Ubiquitous Protein 1 (AUP1)

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