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Tyrosine-Protein Kinase Receptor UFO (AXL) Antibody
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Catalogue No: abx015709
Price:
US$427.75
(Size: 100 µl)
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AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11.Entrez Protein NP_001690.It is a member of the receptor tyrosine kinase subfamily.Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats.It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6.It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding.Alternatively spliced transcript variants encoding different isoforms have been identified.
Research Articles on Tyrosine-Protein Kinase Receptor UFO (AXL)
| Target | Tyrosine-Protein Kinase Receptor UFO (AXL) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P30530 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N5L2, Q9UD27 |
| UniProt Entry Name | UFO_HUMAN |
| Gene Symbol | AXL |
| GeneID | 558 |
| OMIM | 109135 |
| HGNC | 905 |
| KEGG | hsa:558 |
| Ensembl | ENSG00000167601 |
| String | 9606.ENSP00000301178 |
| Molecular Weight | 97.4 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |