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Apoptosis Regulator Bcl-2 (BCL2) Antibody
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Catalogue No: abx002104
Price:
US$203.00
(Size: 20 µl)
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BCL2 Antibody is a Rabbit Polyclonal antibody against BCL2. This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Research Articles on Apoptosis Regulator Bcl-2 (BCL2)
| Target | Apoptosis Regulator Bcl-2 (BCL2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/100, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-239 of human Bcl-2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10415 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JHD5, P10416, Q13842, Q16197 |
| UniProt Entry Name | BCL2_HUMAN |
| Gene Symbol | BCL2 |
| GeneID | 596 |
| OMIM | 151430 |
| NCBI Accession | NP_000624.2 |
| HGNC | 990 |
| KEGG | hsa:596 |
| Ensembl | ENSG00000171791 |
| String | 9606.ENSP00000381185 |
| Molecular Weight | Calculated MW: 26 kDa Observed MW: 26 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |