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B1 Bradykinin Receptor (BDKRB1) Antibody
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Catalogue No: abx034082
Price:
US$326.25
(Size: 80 µl)
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Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Research Articles on B1 Bradykinin Receptor (BDKRB1)
| Target | B1 Bradykinin Receptor (BDKRB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46663 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7F5, Q546S7, Q8N0Y8 |
| UniProt Entry Name | BKRB1_HUMAN |
| KEGG | hsa:623 |
| String | 9606.ENSP00000216629 |
| Molecular Weight | Calculated MW: 40.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |