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Bcl2-Associated Agonist of Cell Death Phospho-Ser161 (BAD pS161) Antibody
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Catalogue No: abx032121
Price:
US$326.25
(Size: 80 µl)
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BAD promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Research Articles on Bcl2-Associated Agonist of Cell Death Phospho-Ser161 (BAD pS161)
| Target | Bcl2-Associated Agonist of Cell Death Phospho-Ser161 (BAD pS161) |
| Clonality | Polyclonal |
| Target Modification | Ser161 |
| Modification | Phosphorylation |
| Reactivity | Mouse |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S161 of mouse BAD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q61337 (UniProt, ExPASy) |
| UniProt Entry Name | BAD_MOUSE |
| KEGG | mmu:12015 |
| String | 10090.ENSMUSP00000025910 |
| Molecular Weight | Calculated MW: 22.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat Bad. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |