Bcl2-Associated Agonist of Cell Death Phospho-Ser91 (BAD pS91) Antibody

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].

Target	Bcl2-Associated Agonist of Cell Death Phospho-Ser91 (BAD pS91)
Clonality	Polyclonal
Target Modification	Ser91
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S91 of human BAD.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92934 (UniProt, ExPASy)
UniProt Secondary AC	O14803, Q6FH21
UniProt Entry Name	BAD_HUMAN
KEGG	hsa:572
String	9606.ENSP00000378040
Molecular Weight	Calculated MW: 18.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bcl2-Associated Agonist of Cell Death Phospho-Ser91 (BAD pS91)

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