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Bcl2-Associated Agonist of Cell Death Phospho-Tyr110 (BAD pY110) Antibody
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Catalogue No: abx032127
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Research Articles on Bcl2-Associated Agonist of Cell Death Phospho-Tyr110 (BAD pY110)
| Target | Bcl2-Associated Agonist of Cell Death Phospho-Tyr110 (BAD pY110) |
| Clonality | Polyclonal |
| Target Modification | Tyr110 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y110 of human BAD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92934 (UniProt, ExPASy) |
| UniProt Secondary AC | O14803, Q6FH21 |
| UniProt Entry Name | BAD_HUMAN |
| KEGG | hsa:572 |
| String | 9606.ENSP00000378040 |
| Molecular Weight | Calculated MW: 18.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat BAD. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |