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BAG Family Molecular Chaperone Regulator 2 (BAG2) Antibody
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Catalogue No: abx027768
Price:
US$326.25
(Size: 80 µl)
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BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].
Research Articles on BAG Family Molecular Chaperone Regulator 2 (BAG2)
| Target | BAG Family Molecular Chaperone Regulator 2 (BAG2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95816 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DXE2, Q08AS9, Q6FID0 |
| UniProt Entry Name | BAG2_HUMAN |
| Gene Symbol | BAG2 |
| KEGG | hsa:9532 |
| String | 9606.ENSP00000359727 |
| Molecular Weight | Calculated MW: 23.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow BAG2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |