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Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
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Catalogue No: abx033929
Price:
US$326.25
(Size: 80 µl)
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BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1) binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Research Articles on Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2)
| Target | Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 492-518 amino acids from the C-terminal region of human BAIAP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQB8 (UniProt, ExPASy) |
| UniProt Secondary AC | O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43 |
| UniProt Entry Name | BAIP2_HUMAN |
| NCBI Accession | NP_001138360.1 NP_006331.1 NP_059344.1 NP_059345.1 |
| String | 9606.ENSP00000316338 |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |