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Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
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Catalogue No: abx004080
Price:
US$203.00
(Size: 20 µl)
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BAIAP2 Antibody is a Rabbit Polyclonal antibody against BAIAP2. The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Research Articles on Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2)
| Target | Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQB8 (UniProt, ExPASy) |
| UniProt Secondary AC | O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43 |
| UniProt Entry Name | BAIP2_HUMAN |
| Gene Symbol | BAIAP2 |
| GeneID | 10458 |
| NCBI Accession | NP_059344.1 |
| String | 9606.ENSP00000316338 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 53/58 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |