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Bcl-2 Homologous Antagonist/Killer (BAK1) Antibody
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Catalogue No: abx000593
Price:
US$203.00
(Size: 20 µl)
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BAK1 Antibody is a Rabbit Polyclonal antibody against BAK1. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Research Articles on Bcl-2 Homologous Antagonist/Killer (BAK1)
| Target | Bcl-2 Homologous Antagonist/Killer (BAK1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Bak. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16611 (UniProt, ExPASy) |
| UniProt Secondary AC | C0H5Y7, Q6I9T6, Q92533 |
| UniProt Entry Name | BAK_HUMAN |
| Gene Symbol | BAK1 |
| GeneID | 578 |
| NCBI Accession | NP_001179.1 |
| KEGG | hsa:578 |
| String | 9606.ENSP00000363591 |
| Molecular Weight | Calculated MW: 23 kDa Observed MW: 25 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |