BMP And Activin Membrane-Bound Inhibitor Homolog (BAMBI) Antibody

BAMBI Antibody is a Rabbit Polyclonal antibody against BAMBI. This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.

Target	BMP And Activin Membrane-Bound Inhibitor Homolog (BAMBI)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-152 of human BAMBI.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13145 (UniProt, ExPASy)
UniProt Entry Name	BAMBI_HUMAN
Gene Symbol	BAMBI
GeneID	25805
NCBI Accession	NP_036474.1
KEGG	hsa:25805
String	9606.ENSP00000364683
Molecular Weight	Calculated MW: 29 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on BMP And Activin Membrane-Bound Inhibitor Homolog (BAMBI)

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