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Bcl2 Associated X Protein (BAX) Antibody
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Catalogue No: abx030365
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Research Articles on Bcl2 Associated X Protein (BAX)
| Target | Bcl2 Associated X Protein (BAX) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 69-98 amino acids from the Central region of human Bax. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q07812 (UniProt, ExPASy) |
| Molecular Weight | Calculated MW: 21.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat BAX. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |