BAX (BH3 Domain Specific) Antibody

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Catalogue No: abx025083
Price: US$326.25
(Size: 80 µl)

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BAX (BH3 Domain Specific) Antibody
BAX (BH3 Domain Specific) Antibody BAX (BH3 Domain Specific) Antibody BAX (BH3 Domain Specific) Antibody

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Datasheet SDS
Bax belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

Target BAX (BH3 Domain Specific)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, FCM
Host Rabbit
Recommended dilutions WB: 1/2000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 41-76 amino acids from human Bax.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07812 (UniProt, ExPASy)
NCBI Accession NP_004315.1 NP_620116.1 NP_620118.1 NP_620119.2
Molecular Weight Calculated MW: 21.2 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow BAX.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on BAX (BH3 Domain Specific)
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