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bcl-2 (pS70) Antibody
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Catalogue No: abx032200
Price:
US$326.25
(Size: 80 µl)
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This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Research Articles on bcl-2 (pS70)
| Target | bcl-2 (pS70) |
| Clonality | Polyclonal |
| Target Modification | Ser70 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, WB, DB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S70 of human bcl-2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10415 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JHD5, P10416, Q13842, Q16197 |
| UniProt Entry Name | BCL2_HUMAN |
| NCBI Accession | NP_000624.2 |
| KEGG | hsa:596 |
| String | 9606.ENSP00000381185 |
| Molecular Weight | Calculated MW: 26.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |