Apoptosis Regulator Bcl-2 (BCL2) Antibody

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Catalogue No: abx034669
Price: US$326.25
(Size: 80 µl)

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Apoptosis Regulator Bcl-2 (BCL2) Antibody
Apoptosis Regulator Bcl-2 (BCL2) Antibody

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Datasheet SDS
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Target Apoptosis Regulator Bcl-2 (BCL2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 49-76 amino acids from the Central region of human Bcl-2.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10415 (UniProt, ExPASy)
UniProt Secondary AC C9JHD5, P10416, Q13842, Q16197
UniProt Entry Name BCL2_HUMAN
Gene Symbol BCL2
GeneID 596
OMIM 151430
HGNC 990
KEGG hsa:596
Ensembl ENSG00000171791
String 9606.ENSP00000381185
Molecular Weight Calculated MW: 26.3 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Apoptosis Regulator Bcl-2 (BCL2)
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