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B-cell Lymphoma 6 (BCL6) Antibody
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Catalogue No: abx005414
Price:
US$217.50
(Size: 20 µl)
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BCL6 Antibody is a Rabbit Polyclonal antibody against BCL6. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Research Articles on B-cell Lymphoma 6 (BCL6)
| Target | B-cell Lymphoma 6 (BCL6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-280 of human BCL6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P41182 (UniProt, ExPASy) |
| UniProt Secondary AC | A7E241, B8PSA7, D3DNV5 |
| UniProt Entry Name | BCL6_HUMAN |
| Gene Symbol | BCL6 |
| GeneID | 604 |
| NCBI Accession | NP_001124317.1 |
| KEGG | hsa:604 |
| String | 9606.ENSP00000384371 |
| Molecular Weight | Calculated MW: 79 kDa Observed MW: 86 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |