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Bestrophin-3 (BEST3) Antibody
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Catalogue No: abx030836
Price:
US$290.00
(Size: 80 µl)
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BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).
Research Articles on Bestrophin-3 (BEST3)
| Target | Bestrophin-3 (BEST3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8N1M1 (UniProt, ExPASy) |
| UniProt Secondary AC | B5MDI8, F8VVZ2, Q53YQ7, Q8N356, Q8NFT9, Q9BR80 |
| UniProt Entry Name | BEST3_HUMAN |
| Gene Symbol | BEST3 |
| KEGG | hsa:144453 |
| String | 9606.ENSP00000332413 |
| Molecular Weight | Calculated MW: 76.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |