Beta-Glucuronidase (GUSB) Antibody

Beta-Glucuronidase (GUSB) Antibody is a Rabbit Polyclonal antibody for the detection of GUSB.

The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It is a tetrameric glycoprotein composed of identical subunits. GUSB plays an important role in the degradation of dermatan and keratan sulfates. GUSB has two isoforms with the molecular mass of 75 kDa and 69 kDa, and it always can be detected as 78 kDa, 60 kDa and 18 kDa.

Target	Beta-Glucuronidase (GUSB)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	glucuronidase, beta
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P08236 (UniProt, ExPASy)
UniProt Secondary AC	B4E1F6, E9PCV0, Q549U0, Q96CL9
UniProt Entry Name	BGLR_HUMAN
Gene Symbol	GUSB
GeneID	2990
OMIM	253220
HGNC	4696
KEGG	hsa:2990
Ensembl	ENSG00000169919
String	9606.ENSP00000302728
Molecular Weight	Observed MW: 78 kDa, 60 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Beta-Glucuronidase (GUSB)

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